Apoquel (oclacitinib) Tablets, 5.4 mg

Apoquel 5.4 mg Tablets for Allergic Dermatitis in Dogs

Apoquel 5.4 mg tablets are a prescription allergy medicine for dogs designed to relieve itching and inflammation caused by allergic dermatitis and atopic dermatitis in dogs. This fast-acting oral tablet works by selectively inhibiting Janus kinase (JAK) enzymes, which are responsible for transmitting itch and inflammation signals in the immune system. 

By blocking these pathways, Apoquel for dogs provides relief within 4 hours and helps manage chronic skin allergies without the side effects commonly associated with steroids.

Unlike corticosteroids or antihistamines, Apoquel effectively reduces symptoms of seasonal, environmental, and food allergies, allowing dogs to experience a better quality of life. Whether your dog suffers from pollen allergies, flea allergies, or contact dermatitis, Apoquel 5.4 mg is a trusted solution for long-term dermatological care.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Also Available In:

Apoquel is available in different strengths to suit dogs of various sizes and needs. Choose the right dosage (from the apoquel dosing chart) based on your veterinarian’s recommendation:

• Apoquel Tablets for Dogs 3.6mg – Ideal for small dogs needing effective allergy and itch relief.
• Apoquel Tablets for Dogs 16mg – Best suited for large dogs requiring stronger dosage control.

Select the appropriate Apoquel strength for your dog and help them live an itch-free, happy life! 

What Are the Benefits of Apoquel 5.4 mg Tablets for Dogs?

Apoquel is a veterinarian-recommended treatment that provides several benefits for dogs suffering from pruritus (itchiness) and allergic skin conditions:

• Fast-Acting Itch Relief – Starts working within 4 hours and provides complete relief in 24 hours.
• Selective Immune Modulation – Targets JAK-1 and JAK-3 enzymes, reducing inflammatory cytokines without affecting overall immune function.
• Steroid-Free Treatment – Unlike prednisone or cyclosporine, Apoquel minimizes side effects like excessive thirst, weight gain, or mood changes.
• Long-Term Allergy Control – Safely used for extended periods without suppressing adrenal function like corticosteroids.
• Versatile Allergy Management – Effective against environmental allergens (pollen, dust mites), food allergies, and flea allergy dermatitis.
• Improves Skin Healing – Reduces constant scratching, chewing, and licking, allowing the skin barrier to restore itself naturally.

Apoquel 5.4 mg is ideal for dogs weighing 6.6-19.9 lbs experiencing moderate to severe allergic reactions.

How to Use Apoquel 5.4 mg for Dogs? (Dosage and Administration)

• Initial Treatment – Administer twice daily for up to 14 days.
• Maintenance Dose – After 14 days, reduce to once daily for ongoing allergy relief.
• Can be given with or without food for ease of administration.
• Always follow your veterinarian’s dosage instructions based on your dog's weight.

💡 Tip: If you miss a dose, administer it as soon as possible. If it's close to the next scheduled dose, skip the missed dose and continue with the regular schedule.

What Are the Active Ingredients in Apoquel 5.4 mg?

Apoquel contains Oclacitinib maleate (5.4 mg) as the active ingredient, a Janus kinase (JAK) inhibitor that blocks itch-inducing and inflammatory cytokines, such as Interleukin-31 (IL-31).

Inactive Ingredients:

• Microcrystalline cellulose – A stabilizing agent.
• Lactose monohydrate – A filler to aid tablet formulation.
• Croscarmellose sodium – Helps the tablet dissolve quickly for fast absorption.
• Magnesium stearate – A lubricant to ensure proper tablet consistency.

Are There Any Side Effects of Apoquel 5.4 mg Tablets?

Apoquel is well-tolerated in most dogs, but some may experience mild or rare side effects, including:

• Gastrointestinal upset – Occasional vomiting or diarrhea (usually resolves on its own).
• Increased susceptibility to infections – Due to immune modulation, some dogs may develop minor skin or ear infections.
• Lethargy or decreased appetite – Rare but possible in sensitive dogs.

When to Contact Your Veterinarian:

• Persistent vomiting, diarrhea, or loss of appetite.
• Unusual skin infections, swelling, or new growths.
• Signs of respiratory infections (coughing, sneezing).

What Are the Warnings and Precautions for Apoquel Use?

• Not for Puppies Under 12 Months: Apoquel should only be used in adult dogs due to potential immune system effects.
• Avoid in Dogs with Cancer or Serious Infections: Since Apoquel modulates immune function, it is not recommended for dogs with pre-existing immune-related conditions.
  
• Use with Caution in Pregnant or Nursing Dogs: The safety of Apoquel in breeding dogs has not been fully established.
  
• Potential Drug Interactions: Do not use Apoquel with other immunosuppressants (such as cyclosporine or corticosteroids) without veterinary supervision.

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